Treatment with Anti-Inflammatory Proteins Following Heart Attack Shows Promise to Reduce the Risk of Further Heart Damage
Two anti-inflammatory molecules reduce the inflammatory response within the injured heart and reduce scarring, according to new research published in The American Journal of Pathology. Research into the protective effects of two anti-inflammatory molecules, transforming growth factor-beta1 (TGF?1) and Heligmosomoides polygyrus TGM (HpTGM), following heart attack found that both proteins reduced the inflammatory response within the injured heart and reduced mature scarring. Anti-inflammatory therapy to treat patients following acute myocardial infarction is an exciting prospect that deserves further translational studies, report investigators in The American Journal of Pathology, published by Elsevier. Patients with acute heart attacks (ST elevation myocardial infarction, or STEMI) are very likely to survive if they undergo timely reopening of the occluded coronary artery (coronary reperfusion) in specialized clinical centers. Despite the given survival rates and major improvements in treatment, progression to heart failure still represents a…


