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Blueprint Medicines Provides 2025 Outlook

Updating peak systemic mastocytosis franchise revenue opportunity to $4 billion, catalyzed by strong AYVAKIT® (avapritinib) launch and evolving SM prevalence estimates.

Expect to achieve $2 billion in AYVAKIT revenue by 2030.

BLU-808 demonstrates wide therapeutic window with rapid, robust and sustained tryptase reductions exceeding 80% in Phase 1 healthy volunteer study.

Kate Haviland, CEO, to present at J.P. Morgan conference on Monday, January 13 at 9:00 a.m. PT (12:00 p.m. ET).