Several biomarkers were discovered in 2024 across various diseases and conditions. Here are some examples:
1. Parkinson’s Disease Biomarker: Researchers discovered a new biomarker for Parkinson’s disease, which can detect the disease in both people with Parkinson’s and individuals not yet diagnosed or exhibiting symptoms but at high risk of developing it. The assay, called the ?-synuclein seeding amplification assay (?Syn-SAA), targets a protein found in the nervous system called alpha synuclein[3][6][12].
2. Hepatocellular Carcinoma Biomarkers: A thesis on biomarkers for hepatocellular carcinoma identified a new protein, thioredoxin reductase 1 (TXNRD1), which can be used for screening and predicting the risk of recurrence after surgical treatment[2].
3. Cardiovascular Disease Biomarkers: A study discovered transcriptomic biomarkers associated with cardiovascular disease, including genes linked to cardiomyopathy, stroke, and atherosclerosis[5].
4. Amyotrophic Lateral Sclerosis (ALS) Biomarkers: Researchers found that blood-based measures, including levels of markers of nerve damage and chemical DNA modifications, can help predict which individuals with ALS will have faster disease progression over time[8].
5. Crohn’s Disease Biomarkers: A new guideline defined the role of biomarkers in Crohn’s disease, highlighting the need for noninvasive biomarkers to guide diagnosis and treatment[11].
6. Skin Carcinoma Biomarkers: Researchers discovered biomarkers that predict response to immunotherapy in skin carcinoma, which can aid in patient selection and treatment decisions[13].
7. Multiple Sclerosis Biomarkers: A study found that cerebrospinal fluid (CSF) biomarkers collected at the time of multiple sclerosis diagnosis can predict disability progression and relapses in relapsing-remitting MS patients[14].
These biomarkers have the potential to revolutionize disease diagnosis, treatment, and management, enabling earlier intervention and more targeted therapies.
[1] Biomarkers US 2024 – Oxford Global https://oxfordglobal.com/biomarkers/events/biomarkers-us-2024
[2] New thesis on biomarkers for hepatocellular carcinoma https://medicalxpress.com/news/2024-06-thesis-biomarkers-hepatocellular-carcinoma.html
[3] Breaking News: Parkinson’s Disease Biomarker Found https://www.michaeljfox.org/news/breaking-news-parkinsons-disease-biomarker-found
[4] Explore the Top 10 Biomarker Trends in 2024 – StartUs Insights https://www.startus-insights.com/innovators-guide/biomarker-trends/
[5] Discovering biomarkers associated and predicting cardiovascular disease with high accuracy using a novel nexus of … https://www.nature.com/articles/s41598-023-50600-8
[6] What You Need to Know about the New Parkinson’s Biomarker https://www.urmc.rochester.edu/news/story/what-you-need-to-know-about-the-new-parkinsons-biomarker
[7] Biomarkers Europe 2024 – Oxford Global https://oxfordglobal.com/biomarkers/events/biomarkers-europe-2024
[8] MDA 2024: Blood biomarkers may help predict ALS progression rates https://alsnewstoday.com/news/mda-2024-blood-biomarkers-may-help-predict-als-progression/
[9] Focus On Biomarkers Research https://www.ninds.nih.gov/current-research/focus-tools-topics/focus-biomarkers-research
[10] Digital biomarkers: 3PM approach revolutionizing chronic disease … https://link.springer.com/article/10.1007/s13167-024-00364-6
[11] New Guideline Defines the Role of Biomarkers in Crohn’s https://www.gastroendonews.com/Multimedia/Article/06-24/biomarkers-Crohn-s-Disease-AGA-guideline-Ashwin-Ananthakrishnan/74135
[12] Researchers Discover Biomarker for Parkinson’s Disease https://www.americanbrainfoundation.org/researchers-discover-biomarker-for-parkinsons-disease/
[13] Researchers discover biomarkers that predict response to … – IDIBELL https://idibell.cat/en/2024/07/researchers-discover-biomarkers-that-predict-response-to-immunotherapy-in-skin-carcinoma/
[14] CSF biomarkers at diagnosis may predict MS prognosis, study finds https://multiplesclerosisnewstoday.com/news-posts/2024/05/20/csf-biomarkers-time-diagnosis-may-predict-ms-prognosis-study/
[15] The Future of Biomarker Discovery | Eureka blog https://www.criver.com/eureka/future-biomarker-discovery
