A new Canadian study of people living with IBD found that approximately half of study participants suffered from suboptimally controlled disease, which can be connected to lower quality of life.1 The study, published in the scientific journal Digestive Diseases and Sciences, found that 52 percent (45/87)* of people living with Crohn’s disease had suboptimally controlled disease, while 43 percent (33/76)* of people living with ulcerative colitis had sub-optimally controlled disease.
The IBD PODCAST study (Proportion Of inadequate Disease Control And Strategy of Treatment in IBD), which was initiated and supported by AbbVie, assessed in a real clinical practice whether patients with IBD were achieving disease control as measured by the STRIDE-II guideline recommendations**, and the impact on their quality of life.2 The Canadian PODCAST study was part of a broader analysis that included over 2,000 patients across 10 countries.2
Study findings showed that approximately half of patients with IBD had suboptimally controlled disease, mainly with respect to longer-term treatment goals of achieving a good quality of life.1
People with suboptimally controlled disease had numerically higher work productivity loss and activity impairment scores.1
The Canadian findings also highlighted an important discordance between physician and patient perceptions of disease control, and disease control based on STRIDE-II recommendations. Both patients and physicians tended to under report patients‘ suboptimally controlled disease. Between 80 to 85 per cent of patients with objectively measured suboptimally controlled disease had either a patient or physician report that the patient’s disease was optimally controlled.1
https://doi.org/10.1007/s10620-024-08313-z.
