Wasatch Biolabs (WBL), a subsidiary of Renew Biotechnologies and a certified Oxford Nanopore Technologies‘ laboratory, launches a proprietary Targeted DNA Methylation Sequencing Service for researchers and clinical service providers.
The technique is amplification and bisulfite conversion free, effectively bypassing the most common limitations of targeted methylation analysis and enabling WBL to create custom methylation panels that target an unprecedented hundreds-to-thousands of genomic loci of interest with an enrichment of 400-2300x
Clinical applications have historically been hindered by available methods to analyze DNA methylation. Bisulfite sequencing, which involves chemical treatment of DNA with sodium bisulfite and PCR amplification, remains the de facto standard for DNA methylation analysis. However, bisulfite conversion is known to damage DNA, and amplification is prone to errors and biases. Because of these limitations, WBL has developed a targeted sequencing protocol that is bisulfite and PCR amplification free.
If you’re interested in using WBL’s services for your own research or clinical diagnostic tests, visit www.wasatchbiolabs.com
